Pyridineis more basic as compared to pyridazine,
pyrimidine and pyrazine because pyridazine, pyrimidine and pyrazine containing
two nitrogen atoms which are exerted inductive effect to each other so
availability of lone pair for donation is less.
But
pyridazineis more basic as expected, it may be due to
electrostatic repulsion of the lone pairs of the vicinal nitrogens. This
repulsion destabilizes the non-protonated structure and therefore makes
protonation easier.
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