We Know that acyl groups or any electron
withdrawing group present at ring which deactivating as result further
substitution does not take place
While in
case of Aniline or its derivatives, the Friedel Craft reaction
occurs in the presence of aluminium chloride which
is Lewis acidic and the Aniline is a strong base.
Therefore, when aniline is reacted with aluminium chloride in Friedel-Craft’s
reaction, formation of salt takes place. On which the presence of positive charge on nitrogen deactivates the benzene ring towards
electrophilic aromatic substitution reactions. Therefore, aniline does not
undergo Friedel-Craft’s reaction
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