This mechanism proceed via carbocation formation and ring expansion mechanism:
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Saturday, January 11, 2020
How to write dehydration and ring expansion mechanism of Tetrahydrofurfuryl alcohol?
This mechanism proceed via carbocation formation and ring expansion mechanism:
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How to write dehydration and ring expansion mechanism of 2-cyclopentylethanol?
This mechanism proceed via carbocation formation and ring expansion mechanism:
Explain Dehydration and ring expansion mechanism of 1-(1-Methylcyclopentyl)ethan-ol?
Write Dehydration and ring expansion mechanism of 1-cyclobutylethanol in the presence of con H2SO4.
Friday, January 10, 2020
Why do not Friedel-Crafts reactions succeed on aromatic rings that are substituted either by a strongly electron-withdrawing group such as carbonyl (C=O) or by an amino group (-NH2, NHR, -NR2):
We Know that acyl groups or any electron
withdrawing group present at ring which deactivating as result further
substitution does not take place
While in
case of Aniline or its derivatives, the Friedel Craft reaction
occurs in the presence of aluminium chloride which
is Lewis acidic and the Aniline is a strong base.
Therefore, when aniline is reacted with aluminium chloride in Friedel-Craft’s
reaction, formation of salt takes place. On which the presence of positive charge on nitrogen deactivates the benzene ring towards
electrophilic aromatic substitution reactions. Therefore, aniline does not
undergo Friedel-Craft’s reaction
Similar
Questions:
Why does not aniline undergo Friedel crafts reactions explain?
We know that
the Friedel Craft reaction occurs in the presence
of aluminium chloride which is Lewis acidic and
the Aniline is a strong base. Therefore, when
aniline is reacted with aluminium chloride in Friedel-Craft’s reaction,
formation of salt takes place. The salt
formation take place as:
The presence
of positive charge on nitrogen deactivates the benzene
ring towards electrophilic aromatic substitution reactions. Therefore, aniline
does not undergo Friedel-Craft’s reaction.
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Questions:
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