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Tuesday, January 28, 2020

What is a haloform reaction?


The oxidative cleavage of Methyl ketones as well as acetaldehyde and 2° terminal alcohol into into a carboxylate anion and a trihalomethane  (haloform) by the reaction of one of halogen in the presence of strong alkali like NaOH or KOH is known as Haloform reaction.

The respective halogen can be chlorine, bromine or iodine.The methyl group of a methyl ketone is converted into an trihalomethane by multiple subsequent steps, that involve formation of an intermediate enolate anion.

Related Questions:
Chlorination of ethane to ethyl chloride is more practicable than chlorination of n-Pentane to 1-Chloropentanc. Why ?

What is the chemical formula of substances which gives a positive iodoform test?

The ketones containing terminal -COCH3 group generally gives positives Iodoform test. For example butan-2-one,  Pentan-2-one, Acetone etc.
It is Most common test for terminal methyl ketones but Iodoform also given by terminal 2° alcohols like Ethanol (CH3CH2OH), Propan-2-ol (CH3CH2(OH) CH3 ), Butan-2-ol, Pentan-2-ol etc
Aldehyde does not gives Iodoform test positive except CH3CHO.
Methylene  active hydrogen containg ketones also gives positive Iodoform test for example  pentane-2,4-dione , Chatechol, and resorcinol etc

Related questions:

Why is the enol form of acetoacetic ester less in percentage than the enol form of acetyl acetone?

Monday, January 27, 2020

What is Chloretone ?

What is Phosgene gas ?

Phosgene is a chlorine containing highly poisonous  gas, which formed by oxidation of chloroform in the presence of oxygen and sunlight.

To prevent the formation of Phosgene from chloroform following measures are taken 
(1) chloroform kept in brown the bottles.
(2) these bottles are filled with capacity to exclude any air.