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Biological Important of Imidazole and structure:

Imidazole and its derivatives form an interesting and important class of heterocyclic aromatic amines.
An imidazole ring is a structural unit in two biologically important compounds, histidine and histamine. 
Histidine is one of the amino acid building blocks of proteins and is directly involved in key proton-transfer processes. The drop in blood pressure associated with shock is a result of the formation of histamine, which stimulates the dilation of blood vessels.

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