Imidazole
and its derivatives form an interesting and important class of heterocyclic aromatic
amines.
An
imidazole ring is a structural unit in two biologically important compounds, histidine
and histamine.
Histidine
is one of the amino acid building blocks of proteins and is directly involved
in key proton-transfer processes. The drop in blood pressure associated with shock
is a result of the formation of histamine, which stimulates the dilation of
blood vessels.
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