Explain Exhaustive alkylation and Hoffmann Elimination.

Then reaction of amines with excess of alkyl halides to form a quaternary ammonium salt is known as exhaustive alkylation and if the alkyl group is methyl, then it is known as exhaustive methylation .

The exhaustive methylation of amine followed by treatment with moist silver oxide (AgO + O2--> AgOH) and subsequent heating to form alkene is known as Hoffmann elimination.

Related Questions:

(1) Explain Dehydration and ring expansion mechanism of 1-(1-Methylcyclopentyl)ethan-ol?

(2) Write Dehydration and ring expansion mechanism of 1-cyclobutylethanol in the presence of con H2SO4.

(3) How to write dehydration and ring expansion mechanism of 2-cyclopentylethanol?

(4) Dehydration of 1-(1-Methylcyclopentyl)ethan-ol follow E1 Elimination Mechanism and take place in the presence concentrate sulphuric acid:

(5) Explain the ring expansion mechanism of Bicyclic 1,2-Diols which undergoes pinacol pinacolone mechanism?

(6) How to write dehydration and ring expansion mechanism of 2-cyclopentylethanol?
(7) Write the major and minor product of hydration of 1-Methylcyclopent-1-ene in acidic medium?

(8) How to write Bechmann rearrangment mechanism involved formation of oxime of cyclohexane and transformation into cyclic amide caprolactam?

(9) Explain Exhaustive alkylation and Hoffmann Elimination.

(10) What is mechanism of exhaustive methylation and Hoffmann elimination of piperidine a secondary amine?

(11)How write mechanism of exhaustive methyl and Hoffmann elimination of ethanamine?

What is Imine-Enamine tautomerism?

An imine is a compound that contains a -C=NH bond. It is homologous of -C=O. And Imime form is just similar to keto form and Enamine form is just similar to Enol form . The Imine-Enamine tautomerism is due to the migration of alpha hydrogen from one polyvalent atom to another to form Enamine thus Imines can be converted into enamines.

Realated Questions:

How many cyclic isomers possible of (C6H12) Hexene?

How many cyclic isomers possible of (C5H10) pentene?

Write the major and minor product of hydration of 1-Methylcyclopent-1-ene in acidic medium?

Why enol form of Beta Dicarbonyl compound more stable than those of monocarbonyl compounds?

Why enol form of phenol is more stable than its keto isomers?

How to write Bechmann rearrangment mechanism involved formation of oxime of cyclohexane and transformation into cyclic amide caprolactam?

This reaction proceed through formation of of oxime cyclohexane by Nucleophilic Addition reaction and followed by Bechmann rearrangment to form desired product Caprolactam , the whole Mechanism given as.

Arrange in correct order of basic Character of aniline, pyrrol, pyridine and piperidine?

We know that  aliphatic amines are more basic than aromatic amines due to non delocalized of lone pair of nitrogen atom hence piperidine (option IV) is more basic than others

Pyridine is more basic than aniline and  pyrrol because is lone pair of nitrogen is does not involved in pi cloud formation that means it is localised while pryrrol is less basic than aniline because is lone pair involved in pi cloud formation of pyrrol ring 

Hence correct basic order is (iV) >(iii)>(I)>(ii)

Related Questions:

Give an explanation for the fact that Guanidine NH=C(CH3)2 is a stronger base than most of amines?

Arrange in correct order of basic Character of aniline, pyrrol, pyridine and piperidine?

What is correct basicity order of pyridine, pyridazine, pyrimidine and pyrazine ?

Why pyridine is more basic than Pyrrole?

Why pyrimidine is less basic than pyridine?

Imidazole is more basic than pyridine? Why?

Biological Important of Imidazole and structure:

Pyridine is almost 1 million times less basic than piperidine? Why?

Cyclohexylamine amine is the stronger base than Aniline? Why?

Tetrahydroquinoline amine is the stronger base than Tetrahydroisoquinoline? Why?

What is correct basicity order of pyridine, pyridazine, pyrimidine and pyrazine ?

Pyridine is more basic as compared to pyridazine, pyrimidine and pyrazine because pyridazine, pyrimidine and pyrazine containing two nitrogen atoms which are exerted inductive effect to each other so availability of lone pair for donation is less.

But pyridazineis  more basic as expected, it may be due to electrostatic repulsion of the lone pairs of the vicinal nitrogens. This repulsion destabilizes the non-protonated structure and therefore makes protonation easier.

Related Questions:

(1) Give an explanation for the fact that Guanidine NH=C(CH3)2 is a stronger base than most of amines?

(2) Arrange in correct order of basic Character of aniline, pyrrol, pyridine and piperidine?

(3) What is correct basicity order of pyridine, pyridazine, pyrimidine and pyrazine ?

(4) Why pyridine is more basic than Pyrrole?

(5) Why pyrimidine is less basic than pyridine?

(6) Imidazole is more basic than pyridine? Why?

(7) Biological Important of Imidazole and structure:

(8) Pyridine is almost 1 million times less basic than piperidine? Why?

(9) Cyclohexylamine amine is the stronger base than Aniline? Why?

(10) Tetrahydroquinoline amine is the stronger base than Tetrahydroisoquinoline? Why?