Why 2,6-Dihydroxybenzoic acid is more acidic than 2-hydroxybenzoic acid followed by benzoic acid ?

Due to intramolecular hydrogen bonding of conjugate base of acid give extra stability to the conjugate base hence acidic strength increase for example salicylic acid (2-hydroxybenzoic acid) is more acidic than benzoic acid and 2,6-Dihydroxybenzoic acid is more acidic than  2-hydroxybenzoic acid.

Related Questions:

1. Highly branched carboxylic acids are less acidic than unbranched acids. Explain why?
2. Benzamide is less easily hydrolysed than methyl benzoate. Why ?
3. Alcohols and Phenols both are acidic but phenols are more acidic. Why?
4. Which is more acidic 2-methyl benzoic acid , 3-methyl benzoic acid or 4-methyl benzoic acid.?
5. Why is o-toluic acid (2-methyl benzoic acid) stronger than benzoic acid ?
6. What is the ortho effect? Why are nearly all ortho substitute benzoic acids (except some groups) stronger acid than benzoic acid?
7. Name of groups which does not show ortho effect in benzoic acid?
8. Why Picric acid (2,4,6-trinitrophenol) is weak acid then expected ?
9. What is Steric Inhibition of Deprotonation effect ? Or SID effect ?
10. Alcohols and Phenols both are acidic but phenols are more acidic. Why?
11. Among orthochlorophenol and orthofluorophenol, which will be a stronger acid and why?
12. Why The phenoxide ion is more stable than phenol ?
13. What is correct acidic strengths order of the haloforms acids ? Give correct explanation.
14. Lower aliphatic acids having 1 to 5 carbons are soluble in water but higher fatty acids having six or more than six carbon are insoluble in water but soluble in alcohol. Explain.
15. Phenoxide ion is more stable than an alkaoxide. why?
16. Why does aqueous sodium bicarbonate solution dissolve carboxylic acids but not phenol though they are also acidic ?
17. Chloroform is more acidic than fluoroform why?
18. Fluorine is more electronegative than chlorine even then, p-flurobenzoic acid is weaker acid than p-chlorobenzoic acid explain ?

How to distinguish primary , secondary and tertiary alcohols ?

Primary, secondary and tertiary alcohols can distinguish by Victor-Meyer's test and Lucas test which are given as:

Related Questions:
Both glucose and fructose are reducing sugars but sucrose is non-reducing in nature. Why?
Fructose contains a keto group, yet it reduces Fehling solution and Tollen's reagent. Why ?
What is Dunstan's test , How can it use for test Glycerol ?
What is luca's reagent and where is luca's reagent uses ?
What is Victory-Meyer's test and how can distinction between 1°, 2° and 3° alcohols by this ?
Benzaldehyde gives a positive test with Tollen's reagent but not with Benedict's and Fehling's solution. Comment why?
Aromatic amines are lesser basic than aliphatic amines.why ?
Which are the compounds gives positive Tollen's test?
What is Tollen's reagent?
What is Carbylamine test or Isocyanide test ?
What is Hinsberg's reagent and where Hinsberg's test use?
N-Ethyl-N-methyl propanamine does not show optical activity why?

What is the Isoelectric points of amino acids?

Isoelectric point (pI): The hydrogen ion concentration at which a particular amino acid does not influence by electric field is known as Iso-electric point (pI).

At isoelectric points:

(1) [cation] = [Anion]

(2) Net charge on particular amino acid is zero.

(3) Maximum concentration of zwiter ion

(1) Isoelectric point (pI) of neutral amino acid (for example alanine) is the average of pKa1 and pKa2. For example pI of alanine calculated as:

          PI= 1/2(pKa1+pKa2)

(2) Isoelectric point (pI) of acidic amino acid is the average of pKa values of two -COOH groups (uncharged) in its acidic form. For example pI of Glutamic acid calculated as:

(3)Isoelectric point (pI) of basic amino acid is the average of pKa values of two positively charged amine groups in its acidic form. For example pI of lysine calculated as:

Notes: Acidic amino acid has lowest pI value while basic amino acid had highest isoelectric point (pI).

Related topic:

Amphoteric salt hydrolysis:

How to calculate Isoelectric point (pI) of acidic and basic amino acids?

Isoelectric point (pI): The hydrogen ion concentration at which a particular amino acid does not influence by electric field is known as Iso-electric point (pI).

At isoelectric points:

(1) [cation] = [Anion]

(2) Net charge on particular amino acid is zero.

(3) Maximum concentration of zwiter ion

(1) Isoelectric point (pI) of neutral amino acid (for example alanine) is the average of pKa1 and pKa2. For example pI of alanine calculated as:

          PI= 1/2(pKa1+pKa2)

(2) Isoelectric point (pI) of acidic amino acid is the average of pKa values of two -COOH groups (uncharged) in its acidic form. For example pI of Glutamic acid calculated as:

(3)Isoelectric point (pI) of basic amino acid is the average of pKa values of two positively charged amine groups in its acidic form. For example pI of lysine calculated as:

Related topic:

Amphoteric salt hydrolysis:

50 ml of C3H8 is mixed with 300 ml of oxygen for complete combustion find out the final volume and volume concentration.

 

Related Questions:

(1) 1 ml of gaseous aliphatic compound CnH3nOm is completely burnt in an excess of O2 and cooled to room temperature. The contraction in volume is..

(2) 1 ml of gaseous aliphatic compound CxHyOz is completely burnt in an excess of O2 and cooled to room temperature. The contraction in volume is..