How is base strength related to the availabihty of the electron-pair?

Base strength depends on the ability of the basic site (which always has an unshared electron pair) to accept a proton. This ability depends on the charge in an anion or electron density in a molecular base. For species with an identical charge, dispersal or delocalization of the electrons from the basic site to other parts of the molecule results in decreased electron density and decreased base strength.

Related Questions:

1. What is relative basic strength order 1° amines , 2°amines and 3° amines ? 
2. Explain:Arrange the following in the increasing order of their acid strength : Methyl amine, Dimethyl amine, Aniline, N-methyl aniline (I.I.T, 1988).
3. What is Carbylamine test or Isocyanide test ?
4. What is Hinsberg's reagent and where Hinsberg's test use?
5. Can we prepare aniline by Gabriel – phthalimide reaction?
6. N-Ethyl-N-methyl propanamine does not show optical activity why?
7. What is relative basic strength order 1° amines , 2°amines and 3° amines ? Explain:
8. Amines are more basic than ammonia why?
9. Give an explanation for the fact that Guanidine NH=C(CH3)2 is a stronger base than most of amines?
10. Arrange in correct order of basic Character of aniline, pyrrol, pyridine and piperidine?
11. What is correct basicity order of pyridine, pyridazine, pyrimidine and pyrazine ?
12. Give an explanation for the fact that Guanidine NH=C(CH3)2 is a stronger base than most of amines?
13. Arrange in correct order of basic Character of aniline, pyrrol, pyridine and piperidine?
14. What is correct basicity order of pyridine, pyridazine, pyrimidine and pyrazine ?
15. Why pyridine is more basic than Pyrrole?
16. Why pyrimidine is less basic than pyridine?
17. Imidazole is more basic than pyridine? Why?
18. Biological Important of Imidazole and structure:
19. Pyridine is almost 1 million times less basic than piperidine? Why?
20. Cyclohexylamine amine is the stronger base than Aniline? Why?
21. Tetrahydroquinoline amine is the stronger base than Tetrahydroisoquinoline? Why?

Alcohols and Phenols both are acidic but phenols are more acidic. Why?

Alcohols and phenols both are acidic in nature because they Liberate H2 with active metals. But alcohols are weaker acids than phenols because,  

(i) Alcohols fail to turn blue litmus red:

(ii) Alcohols fail to neutralize alkalies whereas phenols do so:

(1) Both phenol and phenoxide ions exhibit resonance, whereas alcohols and alkoxide ion do not.
(2) Due to resonance, positive charge 's developed over "O" of phenol this weakens O-H bond and facilitates release of a proton. On the other hand due to electron donating nature of alkyl group -O-H bond is strengthened. Therefore it hinders the release of proton.      

(3) The phenoxide ion is more stable than phenol, due to greater dispersal of negative charge, therefore. Equilibrium get shifted to forward direction. whereas alkoxide ion is less stable than alcohols due to intensification of negative charge, so equilibrium get shifted towards backward direction. Hence phenols are more acidic than alcohols. 

Related Questions:

Benzamide is less easily hydrolysed than methyl benzoate. Why ?

Highly branched carboxylic acids are less acidic than unbranched acids. Explain why?

Phenoxide ion is more stable than an alkaoxide. why?

CCl4 can not be hydrolysed but SiCl4 can be. Why?

Carbon tetrachloride (SiCl4) easily hydrolysed due to availability of vacant d – orbitals in valence shell of their central atom ( Silicon), hence it can easily extend their coordination number beyond four but this is not possible in case of carbon tetrachloride (CCl4) due to absence of vacant d – orbitals in carbon atom.

Related Questions:

(1) What are the SESQUI OXIDES ? give the examples.

(2) Arrange in increasing order of extent of hydrolysis [ CCI4, MgCI2, AICI3, PCl5, SiCI4].

(3) Although Sulphur contain vacant d-orbital but SF6 does not under go hydrolysis. Why ?

(4) CCl4 can not be hydrolysed but SiCl4 can be. Why?

(5) Silianol (SiH3OH) is more acidic than methanol (CH3OH) why?

(6) What happened when Graphite treated concentrated acids like HNO3/HF or KMnO4 ?.

(7) Why Boric acid become strong acid in the presence of cis 1,2-diol or 1,3-diol ?

(6) What is the molecular formula of Borax ?

(9) What is oil of vitriol ?

(11) Is all the C-C bond length in fullerene is equal ?

(12) Why CO2 is a gas, but SiO2 is a high melting solid?.

(13) CCl4 can not be hydrolysed but SiCl4 can be. Why?

(14) Why the C-C bond length in graphite is shorter than C-C bond length of diamond?

(15) How many six membered ( hexagons) and five membered (Pentagons) carbon ring present in (C60) fullerene ?.